Bacopa and Anxiety
 

             
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Bacopa and Anxiety

In 1980, a one month limited clinical trial of 35 patients with diagnosed anxiety disorders was conducted by Singh and Singh. Patients were given 35 ml twice daily of Brahmi syrup (the equivalent of 12 grams of dry crude extract of Bacopa) in divided doses. All patients exhibited marked improvements in levels of anxiety, levels of disability and mental fatigue and enhanced their memory and attention span. In addition, body weight, along with a decrease in respiration rate and systolic blood pressure (Singh RH, Singh L. Studies on the anti-anxiety effect of the Medyha Rasayana drug, Brahmi (Bacopa monniera Wettst.)--Part 1. J Res Ayur Siddha 1980;1:133-148).

A 1998 study involving rats who were given a 25% bacoside A dose of Bacopa extract showed that anxiolytic activity was enhanced as much as if the drug Lorazepam were administered. The treatment with Bacopa extract exhibited none of the side effects of Lorazepam, such as amnesia (Bhattacharya SK, Ghosal S. Anxiolytic activity of a standardized extract of Bacopa monniera in an experimental study. Phytomedicine 1998;5:77-82)

Research Abstracts

Herbal remedies for anxiety - a systematic review of controlled clinical trials.

* Ernst E.

Complementary Medicine Peninsula Medical School, Universities of Exeter Plymouth, UK. edzard.ernst@pms.ac.uk

Anxiety is a prominent indication for herbal medicine. This systematic review was therefore aimed at summarising the evidence for or against the anxiolytic efficacy of such treatments. Six databases were searched for all randomised clinical trials testing herbal monopreparations in the alleviation of anxiety. Seven such studies and one systematic review were located. Eight different herbals were studied. The herbal medicines, which, according to these data are associated with anxiolytic activity in humans, are Piper methysticum and Bacopa monniera. Only for kava were independent replications available. It was concluded that there is a lack of rigorous studies in this area and that only kava has been shown beyond reasonable doubt to have anxiolytic effects in humans.

PMID: 16428031 [PubMed - indexed for MEDLINE]

Research AbstractsBacopa and Epilepsy
 

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